Searchable abstracts of presentations at key conferences on calcified tissues

ba0001pp155 | Cancer and bone: basic, translational and clinical | ECTS2013

Influence of sex steroids on sclerostin levels in patients with prostate cancer

Munoz-Torres Manuel , Reyes-Garcia Rebeca , Garcia-Fontana Beatriz , Morales-Santana Sonia , Varsavsky Mariela , Maria Dolores Aviles-Perez , Garcia-Martin Antonia

There is increasing evidence for the key role of osteocytes in the regulation of bone remodeling. One of the main products of these cells, sclerostin, inhibits bone formation and may also stimulate bone resorption. To our knowledge, there are few data in prostate cancer (PC) patients especially in patients with hypogonadism related to androgen deprivation therapy (ADT). The aim of this study was to compare serum levels of sclerostin in ADT-treated and untreated PC patients wit...